Recombination repair pdf
Academic Press, San Diego. For example, a receptor of recombination repair pdf cell that can receive a signal to stop dividing may malfunction, so the cell ignores the signal and keeps dividing and can form a cancer. Recombination repair pdf importance of HDR can be seen from the fact that the mechanism is conserved throughout evolution. Abstract Homologous recombination HR is required for accurate chromosome segregation during the first meiotic division and constitutes a key repair and tolerance pathway for complex DNA damage, including DNA double-strand breaks, interstrand crosslinks, and DNA gaps.